• Posted: June 01, 2015
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BRCA Challenge

The BRCA Challenge aims to advance understanding of the genetic basis of breast and other cancers using data from around the world.

About this Project

The BRCA Challenge of the Global Alliance for Genomics and Health aims to advance understanding of the genetic basis of breast cancer and other cancers by pooling data on BRCA genetic variants from around the world, bringing together information on sequence variation, phenotype and scientific evidence. Improved understanding of genetic variation in these genes has the potential to improve patient diagnoses and prevention of disease.

Funders

Leadership

  • Sir John Burn
    • Newcastle University
    • Newcastle upon Tyne, United Kingdom
    • Co-Lead, Group
  • Stephen Chanock
    • Co-Lead, Group

Contact Information

Project Details

Related Working Group(s):

DataClinicalRegulatory and Ethics

Team:

  • Rachel Liao , Broad Institute , Cambridge, United States
  • Sir John Burn , Newcastle University , Newcastle upon Tyne, United Kingdom
  • Stephen Chanock , National Cancer Institute , Washington, D.C, United States
  • Antonis Antoniou , University of Cambridge , Cambridge, United Kingdom
  • Lawrence Brody , National Human Genome Research Institute , Washington, D.C, United States
  • Bob Cook-Deegan , Duke University United States
  • Fergus Couch , Mayo Clinic , Minnesota, United States
  • Susan Domchek , University of Pennsylvania , Philadelphia, United States
  • Johan den Dunnen , Leiden University Medical Center , Leiden, Netherlands
  • Douglas Easton , University of Cambridge , Cambridge, United Kingdom
  • William Foulkes , McGill University / Université McGill , Montreal, Canada
  • Judy Garber , Dana Farber Cancer Institute , Boston, United States
  • David Goldgar , Huntsman Cancer Institute , Salt Lake City, United States
  • Kazuto Kato , Osaka University, Graduate School of Medicine , Osaka, Japan
  • Baroness Delyth Morgan , Breast Cancer Now , London, United Kingdom
  • Robert Nussbaum , University of California , San Francisco, United States
  • Kenneth Offit , Memorial Sloan Kettering Cancer Center , New York, United States
  • Sharon Plon , Baylor College of Medicine/ClinVar , Houston, United States
  • Nazneen Rahman , Institute of Cancer Research , London, United Kingdom
  • Heidi Rehm , Harvard Medical School , Boston, United States
  • Mark Robson , Memorial Sloan Kettering Cancer Center , New York, United States
  • Wendy Rubinstein , NIH/NLM/NCBI , Washington, D.C, United States
  • Gunnar Rätsch , Memorial Sloan Kettering Cancer Center , New York, United States
  • Amanda Spurdle , QIMR Berghofer Medical Research Institute , Brisbane, Australia
  • Dominique Stoppa-Lyonnet , Curie Institute , Paris, France
  • Sean Tavtigian , University of Utah , Salt Lake City, United States